Article
BRCA1 and BRCA2 mutations in ethnic Lebanese Arab women with high hereditary risk breast cancer.
The oncologist - 1 Apr 2015
El Saghir Nagi S, Zgheib Nathalie K, Assi Hussein A, Khoury Katia E, Bidet Yannick, Jaber Sara M, Charara Raghid N, Farhat Rania A, Kreidieh Firas Y, Decousus Stephanie, Romero Pierre, Nemer Georges M, Salem Ziad, Shamseddine Ali, Tfayli Arafat, Abbas Jaber, Jamali Faek, Seoud Muhieddine, Armstrong Deborah K, Bignon Yves-Jean, Uhrhammer Nancy
Abstract excerpt
PURPOSE: Breast cancer is the most common malignancy among women in Lebanon and in Arab countries, with 50% of cases presenting before the age of 50 years. METHODS: Between 2009 and 2012, 250 Lebanese women with breast cancer who were considered to be at high risk of carrying BRCA1 or BRCA2 mutations because of presentation at young age and/or positive family history (FH) of breast or ovarian cancer were...
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