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Article

VEGF G-1154A is predictive of severe acute toxicities during chemoradiotherapy for esophageal squamous cell carcinoma in Japanese patients.

Therapeutic drug monitoring - 1 Aug 2008

Sakaeda Toshiyuki, Yamamori Motohiro, Kuwahara Akiko, Hiroe Satoko, Nakamura Tsutomu, Okumura Katsuhiko, Okuno Tatsuya, Miki Ikuya, Chayahara Naoko, Okamura Noboru, Tamura Takao

Abstract excerpt

This study was conducted to evaluate the association between systemic exposure to 5-fluorouracil (5-FU) and genetic polymorphisms of vascular endothelial growth factor (VEGF) with clinical outcomes to a 5-FU/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma (ESCC). Forty-nine patients with ESCC (I/II/III/IVa = 11/9/17/7, with 5 postoperative recurrences) were enrolled...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18641541
DOI: 10.1097/FTD.0b013e318180e3d2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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