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Article

DNA Damage and Repair Capacity in Patients With Lung Cancer: Prediction of Multiple Primary Tumors

17 Jul 2008

Abstract excerpt

PURPOSE: Patients who survive one occurrence of non-small-cell lung cancer (NSCLC) are at higher risk of a second malignancy. Capacity to repair damaged DNA may modulate individual susceptibility to develop lung cancer. Therefore, we evaluated constitutive and induced DNA damage, and repair capacity, in patients with multiple NSCLCs (cases) and compared the results to those obtained in patients with a single...

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Identifiers

PMID: 18640936
DOI: 10.1200/jco.2007.13.2654

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