Article
Characterization of proteoglycan accumulation during formation of cartilagenous tissue in vitro.
Osteoarthritis and cartilage - 1 Jun 1995
Boyle J, Luan B, Cruz T F, Kandel R A
Abstract excerpt
In order to study proteoglycan retention and accumulation, we optimized a chondrocyte cell culture system in which isolated bovine articular chondrocytes accumulate extracellular matrix to form a continuous layer of cartilagenous tissue. The tissue can attain a thickness of up to 110 microns by 3...
Topics
- Animals
- Cartilage, Articular
- Cattle
- Cell Division
- Cells, Cultured
- Collagen
- DNA
- Extracellular Matrix
- Filtration
- Phenotype
- Proteoglycans
