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Article

Characterization of proteoglycan accumulation during formation of cartilagenous tissue in vitro.

Osteoarthritis and cartilage - 1 Jun 1995

Boyle J, Luan B, Cruz T F, Kandel R A

Abstract excerpt

In order to study proteoglycan retention and accumulation, we optimized a chondrocyte cell culture system in which isolated bovine articular chondrocytes accumulate extracellular matrix to form a continuous layer of cartilagenous tissue. The tissue can attain a thickness of up to 110 microns by 35 days. The cells synthesize large keratan sulfate containing proteoglycans and type II collagen indicating that the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 7584317
DOI: 10.1016/s1063-4584(05)80044-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Characterization of proteoglycan accumulation during formation of cartilagenous tissue in vitro.PMID 7584317Read ↗

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