Blood and beyond: Properties of circulating and tissue‐resident human virus‐specific αβ CD8+ T cells

Abstract excerpt

CD8(+) αβ T-cell responses form an essential line of defence against viral infections. An important part of the mechanisms that control the generation and maintenance of these responses have been elucidated in experimental mouse models. In recent years it has become clear that CD8(+) T-cell responses in humans not only show similarities, but also display differences to those occurring in mice. Furthermore, while...

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