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Article

Genetic analysis of 56 polymorphisms in 17 genes involved in methionine metabolism in patients with abdominal aortic aneurysm.

Journal of medical genetics - 1 Nov 2008

Giusti B, Saracini C, Bolli P, Magi A, Sestini I, Sticchi E, Pratesi G, Pulli R, Pratesi C, Abbate R

Abstract excerpt

BACKGROUND: Previous studies suggested an association between abdominal aortic aneurysm (AAA) and hyperhomocysteinaemia, a complex trait determined by genetic and environmental factors. Our hypothesis was that polymorphisms in genes directly or indirectly involved in methionine metabolism may contribute to AAA susceptibility. METHOD: We studied 56 polymorphisms in MTHFR, MTR, MTRR, CBS, MTHFD1, SLC19A1, NNMT,...

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Topics

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Share to Aortic Aneurysm, Abdominal
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Haplotypes

Share to Homocysteine

Share to Linkage Disequilibrium

Share to Methionine

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Source

Identifiers

PMID: 18635682
DOI: 10.1136/jmg.2008.057851

Genes

MTHFD1
AHCY
FOLH1
MTR
MTRR
NNMT
PON1
TYMS
BHMT
BHMT2
CBS
ENOSF1
MTHFR
PON2
SHMT1
TCN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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