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Article

Increased risk of the abdominal aortic aneurysm in carriers of the MTHFR 677T allele.

Journal of applied genetics - 1 Jan 2003

Strauss Ewa, Waliszewski Krzysztof, Gabriel Marcin, Zapalski Stanisław, Pawlak Andrzej L

Abstract excerpt

Abdominal aortic aneurysm (AAA) presents itself as a progressive dilation of the abdominal aorta, leading--if untreated--to rupture. It is a common disease of the elderly, with a complex etiology. Several genetic, biochemical and environmental factors are recognized as relevant for the pathogenesis of AAA. We determined the polymorphism of the MTHFR (methylenetetrahydrofolate reductase) gene within the fourth...

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Share to Aged, 80 and over
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Share to Aortic Aneurysm, Abdominal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Share to Oxidoreductases Acting on CH-NH Group Donors

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 12590185

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Increased risk of the abdominal aortic aneurysm in carriers of the MTHFR 677T allele.PMID 12590185Read ↗

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