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Article

Regulation of MMP-9 by p53 in first trimester cytotrophoblastic cells.

Human reproduction (Oxford, England) - 1 Oct 2008

Cohen M, Wuillemin C, Irion O, Bischof P

Abstract excerpt

BACKGROUND: The matrix metalloproteinase (MMP) family is known to play a key role in tissue remodelling during embryonic development and in pathological conditions, such as cardiovascular disease, arthritis and cancer metastasis. It has been shown previously that p53 regulates positively or negatively the expression of different MMPs. Because of p53 overexpression in trophoblastic cells, and its potential role in...

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PMID: 18635530
DOI: 10.1093/humrep/den264
PMCID: PMC2538584

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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