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Article

Genome-wide RNAi screen for host factors required for intracellular bacterial infection.

Science (New York, N.Y.) - 19 Aug 2005

Agaisse Hervé, Burrack Laura S, Philips Jennifer A, Rubin Eric J, Perrimon Norbert, Higgins Darren E

Abstract excerpt

Most studies of host-pathogen interactions have focused on pathogen-specific virulence determinants. Here, we report a genome-wide RNA interference screen to identify host factors required for intracellular bacterial pathogenesis. Using Drosophila cells and the cytosolic pathogen Listeria monocyt...

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PMID: 16020693
DOI: 10.1126/science.1116008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16020693-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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