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Article

Molecular analysis of multifocal papillary thyroid carcinoma

15 Jul 2008

Abstract excerpt

Papillary thyroid carcinoma (PTC) frequently presents as a multifocal process. To study the importance of separating independent primary (IP) from intrathyroid metastatic (ITM) PTC, we examined 19 molecular markers on 42 separate tumors from 18 multifocal PTC cases. In 12 of 18 (66.7%) cases, including 6 of 12 (50%) papillary microcarcinoma cases, the same or similar profile of loss of heterozygosities (LOH) and...

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PMID: 18628356
DOI: 10.1677/jme-08-0063

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