Article
A combined molecular-pathologic score improves risk stratification of thyroid papillary microcarcinoma.
Cancer - 15 Apr 2012
Niemeier Leo A, Kuffner Akatsu Haruko, Song Chi, Carty Sally E, Hodak Steven P, Yip Linwah, Ferris Robert L, Tseng George C, Seethala Raja R, Lebeau Shane O, Stang Michael T, Coyne Christopher, Johnson Jonas T, Stewart Andrew F, Nikiforov Yuri E
Abstract excerpt
BACKGROUND: Thyroid papillary microcarcinoma (TPMC) is an incidentally discovered papillary carcinoma that measures ≤1.0 cm in size. Most TPMCs are indolent, whereas some behave aggressively. The objective of the study was to evaluate whether the combination of v-raf murine sarcoma viral oncogene homolog B1 (BRAF) mutation and specific histopathologic features allows risk stratification of TPMC. METHODS: A group...
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