Article
The DLC-1 -29A/T polymorphism is not associated with nasopharyngeal carcinoma risk in Chinese population.
Genetic testing - 1 Sept 2008
Feng Xiang-Ling, Zhou Wen, Li Hong, Fang Wei-Yi, Zhou Yi-Bo, Yao Kai-Tai, Ren Cai-Ping
Abstract excerpt
Deleted in liver cancer-1 (DLC-1), encoding a Rho GTPase-activating protein (GAP), is considered as a promising candidate tumor suppressor gene in nasopharyngeal carcinoma (NPC). The single-nucleotide polymorphism (SNP) -29A/T upstream of ATG start codon was found when gene mutation profile of DLC-1 in NPC was analyzed. To evaluate the correlation between SNP -29A/T in the promoter region of DLC-1 gene and risk...
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