Detection of burst-promoting activity in spleens of myeloproliferative sarcoma virus-infected mice using serum-free cultures.

doi:10.1111/j.1440-1827.1991.tb03353.x

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Article

Detection of burst-promoting activity in spleens of myeloproliferative sarcoma virus-infected mice using serum-free cultures.

Acta pathologica japonica - 1 Apr 1991

Matsuo K, Oda H, Fukushima T, Matsuoka J, Hashimoto N, Tadokoro K, Kohama H, Sato M, Jasmin C, Urano Y

Abstract excerpt

Myeloproliferative syndrome was induced in adult DBA/2 mice by inoculation with myeloproliferative sarcoma virus (MPSV) and Friend murine leukemia virus (F-MuLV) as a helper virus. On day 26 after infection, the spleen weighed a maximum of 2.0 g (about 30 times the control weight). Assay of multipotent stem cells in vitro showed that the more enlarged spleens contained an increased number and concentration of...

Topics

Animals
Chromatography, Ion Exchange
Colony-Forming Units Assay
Erythroid Precursor Cells
Erythropoietin
Female
Genetic Variation
Hematopoiesis
Hematopoietic Stem Cells
Interleukin-3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice

Moloney murine sarcoma virus

Recombinant Proteins

Sarcoma, Experimental

Splenic Neoplasms

Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 1862706
DOI: 10.1111/j.1440-1827.1991.tb03353.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1862706-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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