Article
Genes and type 2 diabetes mellitus.
Current diabetes reports - 1 Jun 2008
Groop Leif, Lyssenko Valeriya
Abstract excerpt
In 2007, five whole genome-wide association studies were published on the genetics of type 2 diabetes mellitus (T2DM), followed by the discovery of 11 genes consistently associated with T2DM. This breakthrough provided the first glimpses of a complete picture of the disease's genetic complexity. Currently, we are only beginning to understand how DNA methylation, histone acetylation, and deacetylation may...
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