Surface IgG content of murine hybridomas: Direct evidence for variation of antibody secretion rates during the cell cycle

Abstract excerpt

Previous experiments have shown that population average surface lgG content is correlated with the specific antibody production rates of batch hybridoma cultures. Therefore, surface associated lgG content of single hybridoma cells might indicate antibody secretion rates of individual cells. Moreover, the surface lgG content should reflect the pattern of secretion rates during the cell cycle. To probe for lgG...

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