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Article

Role of extracellular glutamic acids in the stability and energy landscape of bacteriorhodopsin.

Biophysical journal - 1 Oct 2008

Sapra K Tanuj, Doehner Jana, Renugopalakrishnan V, Padrós Esteve, Muller Daniel J

Abstract excerpt

Bacteriorhodopsin (BR), a specialized nanomachine, converts light energy into a proton gradient to power Halobacterium salinarum. In this work, we analyze the mechanical stability of a BR triple mutant in which three key extracellular residues, Glu(9), Glu(194), and Glu(204), were mutated simultaneously to Gln. These three Glu residues are involved in a network of hydrogen bonds, in cation binding, and form part...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18621827
DOI: 10.1529/biophysj.108.131904
PMCID: PMC2547453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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