Article
Structure of the bacteriorhodopsin mutant F219L N intermediate revealed by electron crystallography.
The EMBO journal - 15 May 2000
Vonck J
Abstract excerpt
Bacteriorhodopsin is a light-driven proton pump in halobacteria that forms crystalline patches in the cell membrane. Isomerization of the bound retinal initiates a photocycle resulting in the extrusion of a proton. An electron crystallographic analysis of the N intermediate from the mutant F219L gives a three-dimensional view of the large conformational change that occurs on the cytoplasmic side after...
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