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Article

Type 2 diabetes significantly modulates the cardiovascular risk conferred by the PAI-1 -675 4G/5G polymorphism in angiographied coronary patients.

Clinica chimica acta; international journal of clinical chemistry - 1 Oct 2008

Saely Christoph H, Muendlein Axel, Vonbank Alexander, Sonderegger Gudrun, Aczel Stefan, Rein Philipp, Risch Lorenz, Drexel Heinz

Abstract excerpt

BACKGROUND: The association of the -675 4G/5G polymorphism of the plasminogen activator inhibitor-1 (PAI-1) gene with cardiovascular disease in patients with type 2 diabetes (T2DM) is unknown. METHODS: Genotyping was performed in 672 consecutive Caucasian patients undergoing coronary angiography for the evaluation of stable coronary artery disease (CAD). Vascular events were recorded over 4 years. RESULTS: In...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18619429
DOI: 10.1016/j.cca.2008.06.015

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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