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Article

The role of 3D microenvironmental organization in MCF-7 epithelial-mesenchymal transition after 7 culture days.

Experimental cell research - 10 Jun 2013

Foroni Laura, Vasuri Francesco, Valente Sabrina, Gualandi Chiara, Focarete Maria Letizia, Caprara Giacomo, Scandola Mariastella, D'Errico-Grigioni Antonia, Pasquinelli Gianandrea

Abstract excerpt

We present a multi-technique study on in vitro epithelial-mesenchymal transition (EMT) in human MCF-7 cells cultured on electrospun scaffolds of poly(l-lactic acid) (PLA), with random and aligned fiber orientations. Our aim is to investigate the morphological and genetic characteristics induced by extracellular matrix in tumor cells cultured in different 3D environments, and at different time points. Cell...

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Identifiers

PMID: 23583658
DOI: 10.1016/j.yexcr.2013.03.035

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SMAD2
SOX10
TFPI2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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