Article
kDNA gene signatures of Trypanosoma cruzi in blood and oesophageal mucosa from chronic chagasic patients.
Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Nov 2008
Manoel-Caetano Fernanda da Silva, Carareto Cláudia Márcia Aparecida, Borim Aldenis Albaneze, Miyazaki Kenji, Silva Ana Elizabete
Abstract excerpt
Trypanosoma cruzi presents a high degree of intraspecific variability, with possible implications for the pathogenesis of Chagas disease. The aim of this study was to evaluate T. cruzi kDNA minicircle gene signatures using the low-stringency single-specific-primer PCR technique in both peripheral blood and oesophageal mucosa from chronic chagasic patients, with or without megaesophagus, alone or in combination...
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