Article
Lineage analysis of circulating Trypanosoma cruzi parasites and their association with clinical forms of Chagas disease in Bolivia.
PLoS neglected tropical diseases - 18 May 2010
del Puerto Ramona, Nishizawa Juan Eiki, Kikuchi Mihoko, Iihoshi Naomi, Roca Yelin, Avilas Cinthia, Gianella Alberto, Lora Javier, Velarde Freddy Udalrico Gutierrez, Renjel Luis Alberto, Miura Sachio, Higo Hiroo, Komiya Norihiro, Maemura Koji, Hirayama Kenji
Abstract excerpt
BACKGROUND: The causative agent of Chagas disease, Trypanosoma cruzi, is divided into 6 Discrete Typing Units (DTU): Tc I, IIa, IIb, IIc, IId and IIe. In order to assess the relative pathogenicities of different DTUs, blood samples from three different clinical groups of chronic Chagas disease patients (indeterminate, cardiac, megacolon) from Bolivia were analyzed for their circulating parasites lineages using...
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