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Article

Capillary gel electrophoresis: a simple method for identification of mutations and polymorphisms in the CEBPA gene in patients with acute myeloid leukaemia.

European journal of haematology - 1 Oct 2008

Juhl-Christensen Caroline, Bomberg Marianne, Melsvik Dorte, Hokland Peter, Nyvold Charlotte Guldborg

Abstract excerpt

INTRODUCTION: The CEBPA gene encodes a transcription factor, CCAAT/enhancer binding protein (C/EBP)alpha. Expression of the wildtype protein is essential for the lineage specific differentiation of myelocytic haematopoietic precursors into mature neutrophils. Eight percentage of all AML patients harbour at least one mutation in this gene, increasing up to 15% in the group, where standard karyotypic analysis do...

Read the complete abstract on PubMed

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Share to CCAAT-Enhancer-Binding Proteins
Share to EBP gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Leukemic

Share to Leukemia, Myeloid, Acute

Share to Mutation

Share to Myeloid Progenitor Cells

Share to Polymorphism, Genetic

Share to Predictive Value of Tests

Source

Identifiers

PMID: 18616509
DOI: 10.1111/j.1600-0609.2008.01117.x

Genes

EBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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