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Article

Genetic variations of Mrf-2/ARID5B confer risk of coronary atherosclerosis in the Japanese population.

International heart journal - 1 May 2008

Wang Guoqin, Watanabe Masafumi, Imai Yasushi, Hara Kazuo, Manabe Ichiro, Maemura Koji, Horikoshi Momoko, Kohro Takahide, Amiya Eisuke, Sugiyama Takao, Fujita Takeshi, Kadowaki Takashi, Yamazaki Tsutomu, Nagai Ryozo

Abstract excerpt

A phenotypic change of smooth muscle cells (SMCs) is considered to be critical in the pathogenesis of atherosclerotic lesions such as coronary artery disease (CAD). Mrf-2/ARID5B, a member of the AT-rich interaction domain family of transcription factors, is highly expressed in the cardiovascular system and is believed to play essential roles in the phenotypic change of SMCs through its regulation of SMC...

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Identifiers

PMID: 18612189
DOI: 10.1536/ihj.49.313

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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