Article
Associations of variations in the MRF2/ARID5B gene with susceptibility to type 2 diabetes in the Japanese population.
Journal of human genetics - 26 Nov 2012
Wang Guoqin, Watanabe Masafumi, Imai Yasushi, Hara Kazuo, Manabe Ichiro, Maemura Koji, Horikoshi Momoko, Ozeki Atsuko, Itoh Chikako, Sugiyama Takao, Kadowaki Takashi, Yamazaki Tsutomu, Nagai Ryozo
Abstract excerpt
Modulator recognition factor-2 (Mrf2/AT-rich interaction domain (Arid)5b) has been revealed to be involved in pathogenesis of atherosclerosis and adipogenesis. Single-nucleotide polymorphisms (SNPs) in the MRF2/ARID5B gene are associated with coronary artery disease (CAD) and has been proposed as a candidate gene for type 2 diabetes (T2D). The study was aimed to determine whether any of the four MRF2/ARID5B SNPs...
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