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Article

Genetic variation in candidate obesity genes ADRB2, ADRB3, GHRL, HSD11B1, IRS1, IRS2, and SHC1 and risk for breast cancer in the Cancer Prevention Study II.

Breast cancer research : BCR - 1 Jan 2008

Feigelson Heather Spencer, Teras Lauren R, Diver W Ryan, Tang Weining, Patel Alpa V, Stevens Victoria L, Calle Eugenia E, Thun Michael J, Bouzyk Mark

Abstract excerpt

INTRODUCTION: Obesity has consistently been associated with postmenopausal breast cancer risk. Proteins that are secreted by adipose tissue or are involved in regulating body mass may play a role in breast tumor development. METHODS: We conducted a nested case-control study among postmenopausal women from the American Cancer Society Cancer Prevention Study II Nutrition Cohort to determine whether genes associated...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18611262
DOI: 10.1186/bcr2114
PMCID: PMC2575528

Genes

IRS2
ADRB2
ADRB3
GHRL
IRS1
SHC1
CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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