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Article

Exome sequencing of a large family identifies potential candidate genes contributing risk to bipolar disorder.

Gene - 1 Mar 2018

Zhang Tianxiao, Hou Liping, Chen David T, McMahon Francis J, Wang Jen-Chyong, Rice John P

Abstract excerpt

Bipolar disorder is a mental illness with lifetime prevalence of about 1%. Previous genetic studies have identified multiple chromosomal linkage regions and candidate genes that might be associated with bipolar disorder. The present study aimed to identify potential susceptibility variants for bipolar disorder using 6 related case samples from a four-generation family. A combination of exome sequencing and...

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PMID: 29248581
DOI: 10.1016/j.gene.2017.12.025
PMCID: PMC6040674

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