Article
Lack of multiple copies of pfmdr1 gene in Papua New Guinea.
Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Nov 2008
Hodel Eva Maria, Marfurt Jutta, Müller Dania, Rippert Anja, Borrmann Steffen, Müller Ivo, Reeder John C, Siba Peter, Genton Blaise, Beck Hans-Peter
Abstract excerpt
We describe here the results of an analysis of Plasmodium falciparum multidrug resistance protein 1 (pfmdr1) gene copy number from 440 field isolates from Papua New Guinea. No multiple copies of the gene were found, which corresponds to the lack of usage of mefloquine. These data extend regional knowledge about the distribution of multidrug-resistant P. falciparum.
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