Article
[Assessment of sensitivity of commercial test-systems for HBsAg immunodetection according to their ability to detect HBsAg-mutants of hepatitis B virus].
Zhurnal mikrobiologii, epidemiologii i immunobiologii - 1 Jan 2000
Bazhenov A I, Konopleva M V, Fel'dsherova A A, El'gort D A, Khats Iu S, Lapina N E, Godkov M A, Suslov A P
Abstract excerpt
Comparative study of widely distributed on Russian market commercial test-systems for HBsAg detection by enzyme immunoassay was performed. Panel of serum samples containing mutant forms of HBsAg was developed for the study. It showed that only 2 out of 7 studied test-systems are able to detect mutant forms of HBsAg with the same sensitivity as "wild-type" forms of HBsAg. Test-systems based only on monoclonal...
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