Article
Analysis of natural sequence variation and covariation in human immunodeficiency virus type 1 integrase.
Journal of virology - 1 Sept 2008
Myers Richard E, Pillay Deenan
Abstract excerpt
Human immunodeficiency virus type 1 (HIV-1) integrase inhibitors are in clinical trials, and raltegravir and elvitegravir are likely to be the first licensed drugs of this novel class of HIV antivirals. Understanding resistance to these inhibitors is important to maximize their efficacy. It has b...
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