Article
HFE C282Y homozygotes have reduced low-density lipoprotein cholesterol: the Atherosclerosis Risk in Communities (ARIC) Study.
Translational research : the journal of laboratory and clinical medicine - 1 Jul 2008
Pankow James S, Boerwinkle Eric, Adams Paul C, Guallar Eliseo, Leiendecker-Foster Catherine, Rogowski Jason, Eckfeldt John H
Abstract excerpt
Recent studies have raised questions about the long-term health risks for individuals with mutations in the HFE gene, although previous studies may have been plagued by selection bias or lack of population-based comparison groups. We examined cardiovascular disease risk factors and iron and liver biomarkers, as well as morbidity and mortality associated with the C282Y and H63D variants of HFE in the...
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