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Article

Screening for iron overload: lessons from the hemochromatosis and iron overload screening (HEIRS) study.

Canadian journal of gastroenterology = Journal canadien de gastroenterologie - 1 Nov 2009

Adams Paul, Barton James C, McLaren Gordon D, Acton Ronald T, Speechley Mark, McLaren Christine E, Reboussin David M, Leiendecker-Foster Catherine, Harris Emily L, Snively Beverly M, Vogt Thomas, Sholinsky Phyliss, Thomson Elizabeth, Dawkins Fitzroy W, Gordeuk Victor R, Eckfeldt John H

Abstract excerpt

BACKGROUND: The HEmochromatosis and IRon Overload Screening (HEIRS) Study provided data on a racially, ethnically and geographically diverse cohort of participants in North America screened from primary care populations. METHODS: A total of 101,168 participants were screened by testing for HFE C282Y and H63D mutations, and measuring serum ferritin concentration and transferrin saturation. In the present review,...

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Identifiers

PMID: 19893773
DOI: 10.1155/2009/839308
PMCID: PMC2777090

Genes

HFE

Variants

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Screening for iron overload: lessons from the hemochromatosis and iron overload screening (HEIRS) study.PMID 19893773Read ↗

Hemochromatosis and iron-overload screening in a racially diverse population.Semantic proximity Read ↗

Hereditary hemochromatosis: insights from the Hemochromatosis and Iron Overload Screening (HEIRS) Study.Semantic proximity Read ↗

Hemochromatosis and Iron Overload Screening (HEIRS) study design for an evaluation of 100,000 primary care-based adults.Semantic proximity Read ↗

Screening for hemochromatosis: patients with liver disease, families, and populations.Semantic proximity Read ↗

Characteristics of participants with self-reported hemochromatosis or iron overload at HEIRS study initial screening.Semantic proximity Read ↗

Epidemiology and diagnostic testing for hemochromatosis and iron overload.Semantic proximity Read ↗

Iron overload phenotypes and HFE genotypes in white hemochromatosis and iron overload screening study participants without HFE p.C282Y/p.C282Y.Semantic proximity Read ↗

Clinical manifestations of hemochromatosis in HFE C282Y homozygotes identified by screening.Semantic proximity Read ↗

HFE-associated hereditary hemochromatosis: overview of genetics and clinical implications for nurse practitioners in primary care settings.Semantic proximity Read ↗

Serum ferritin concentrations and body iron stores in a multicenter, multiethnic primary-care population.Semantic proximity Read ↗

HFE mutations in Caucasian participants of the Hemochromatosis and Iron Overload Screening study with serum ferritin level <1000 µg/L.Semantic proximity Read ↗

HFE hemochromatosis in African Americans: Prevalence estimates of iron overload and iron overload-related disease.Semantic proximity Read ↗

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