Article
Sex difference in the association of the angiotensin converting enzyme I/D polymorphism and body mass index.
Medical science monitor : international medical journal of experimental and clinical research - 1 Jul 2008
Wacker Michael J, Godard Michael P, McCabe Everlee H, Donnelly Joseph E, Kelly John K
Abstract excerpt
BACKGROUND: Angiotensin converting enzyme (ACE) catayzes the formation of angiotensin I to angiotensin II. A polymorphism has been identified in intron 16 in which a 287 base-pair alu sequence was found to be present (insertion or I) or absent (deletion or D) in the population. ACE and the components of the renin-angiotensin system are expressed in adipose tissue and therefore the I/D polymorphism within ACE may...
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