Article
Fas promoter polymorphisms: genetic predisposition to sarcoidosis in African-Americans.
Tissue antigens - 1 Jul 2008
Wasfi Y S, Silveira L J, Jonth A, Hokanson J E, Fingerlin T, Sato H, Parsons C E, Lympany P, Welsh K, du Bois R M, Newman L S, Maier L A
Abstract excerpt
Apoptosis may perpetuate some forms of inflammation. Of the apoptotic pathway proteins, Fas is particularly overexpressed in sarcoidosis. We hypothesized that Fas promoter single nucleotide polymorphisms (SNPs) contribute to the development and severity of sarcoidosis. Associations of known Fas p...
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