Article
The influence of T cell receptor and cytokine genes on sarcoidosis susceptibility in African Americans.
Human immunology - 1 Sept 1999
Rybicki B A, Maliarik M J, Malvitz E, Sheffer R G, Major M, Popovich J, Iannuzzi M C
Abstract excerpt
The pathogenesis of sarcoidosis, a multisystem granulomatous disorder, is mediated through immunoregulatory pathways. While sarcoidosis clusters in families, inherited risk factors remain undefined. In search of possible sarcoidosis susceptibility genes, we examined anonymous polymorphic genetic markers tightly linked to six different candidate gene regions on chromosomes 2q13, 5q31, 6p23-25, 7p14-15, 14q11 and...
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