Article
Human herpesvirus-8 infection of primary pulmonary microvascular endothelial cells.
American journal of respiratory cell and molecular biology - 1 Dec 2008
Bull Todd M, Meadows Christina A, Coldren Christopher D, Moore Mark, Sotto-Santiago Sylk M, Nana-Sinkam Serge P, Campbell Thomas B, Geraci Mark W
Abstract excerpt
Human herpesvirus-8 (HHV-8) is the causative agent of Kaposi's sarcoma and is associated with the angioproliferative disorders primary effusion lymphoma and multicentric Castleman's disease. Evidence of HHV-8 infection within the pulmonary vasculature of patients with idiopathic pulmonary arterial hypertension (IPAH) has been described. We hypothesize that HHV-8 infection of pulmonary microvascular endothelial...
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