Article
Combined effects of peroxisome proliferator-activated receptor alpha and apolipoprotein E polymorphisms on risk of breast cancer in a Taiwanese population.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Dec 2012
Wu Chen Teng, Cheng Ya-Hsin, Chen Fei-Na, Chen Dar-Ren, Wei Ming Feng, Chang Nai-Wen
Abstract excerpt
BACKGROUND: The peroxisome proliferator-activated receptor alpha (PPARA) and apolipoprotein E (APOE) proteins are reported to be correlated with lipid metabolism, cardiovascular disease, and breast cancer. METHODS: We screened APOE and PPARA (S24F and V227A) polymorphisms in 306 breast cancer patients and 300 noncancer controls and determined the relationship between their genetic polymorphisms and breast cancer...
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