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Article

Immunohistochemical analysis of phosphorylated epidermal growth factor receptor might provide a surrogate marker of EGFR mutation.

Lung cancer (Amsterdam, Netherlands) - 1 Feb 2009

Endoh Hideki, Ishibashi Yasunori, Yamaki Ei, Yoshida Takeshi, Yajima Toshiki, Kimura Hitoshi, Kosaka Takayuki, Onozato Ryoichi, Tanaka Shigebumi, Mitsudomi Tetsuya, Kuwano Hiroyuki

Abstract excerpt

PURPOSE: Overexpression of EGFR is found in several malignancies including lung cancers. Recently, EGFR mutation has been shown to correlate with responsiveness to tyrosine kinase inhibitors (TKI). Although antibodies against phophorylated EGFR have been used in vitro, phosphorylated EGFR has yet not been examined well in resected non-small cell lung cancers (NSCLCs). EXPERIMENTAL DESIGN: We studied the...

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Identifiers

PMID: 18585821
DOI: 10.1016/j.lungcan.2008.05.013

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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