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Article

Role of human aquaporin 5 in colorectal carcinogenesis.

The American journal of pathology - 1 Aug 2008

Kang Sung Koo, Chae Young Kwang, Woo Janghee, Kim Myoung Sook, Park Jong Chul, Lee Juna, Soria Jean Charles, Jang Se Jin, Sidransky David, Moon Chulso

Abstract excerpt

While overexpression of several aquaporins (AQPs) has been reported in different types of human cancer, the role of AQPs in carcinogenesis has not been clearly defined. Here, by immunochemistry, we have found expression of AQP5 protein in 62.8% (59/94) of resected colon cancer tissue samples as well as association of AQP5 with liver metastasis. We then demonstrated that overexpression of human AQP5 (hAQP5)...

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Topics

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Share to Cell Proliferation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colonic Neoplasms

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Share to Cyclin-Dependent Kinase 4

Share to Extracellular Signal-Regulated MAP Kinases

Share to Liver Neoplasms

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Source

Open in PubMed Open full text

Identifiers

PMID: 18583321
DOI: 10.2353/ajpath.2008.071198
PMCID: PMC2475788

Genes

AQP5
AQP1
AQP3
CDK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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