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Article

Plasma Membrane Abundance of Human Aquaporin 5 Is Dynamically Regulated by Multiple Pathways.

PloS one - 1 Jan 2015

Kitchen Philip, Öberg Fredrik, Sjöhamn Jennie, Hedfalk Kristina, Bill Roslyn M, Conner Alex C, Conner Matthew T, Törnroth-Horsefield Susanna

Abstract excerpt

Aquaporin membrane protein channels mediate cellular water flow. Human aquaporin 5 (AQP5) is highly expressed in the respiratory system and secretory glands where it facilitates the osmotically-driven generation of pulmonary secretions, saliva, sweat and tears. Dysfunctional trafficking of AQP5 has been implicated in several human disease states, including Sjögren's syndrome, bronchitis and cystic fibrosis. In...

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Identifiers

PMID: 26569106
DOI: 10.1371/journal.pone.0143027
PMCID: PMC4646687

Genes

AQP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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