Article
Modularity in the genetic disease-phenotype network.
FEBS letters - 23 Jul 2008
Jiang Xingpeng, Liu Bing, Jiang Jiefeng, Zhao Huizhi, Fan Ming, Zhang Jing, Fan Zhenjie, Jiang Tianzi
Abstract excerpt
Similar disease phenotypes are engendered as a result of the modular nature of gene networks; thus we hypothesized that all human genetic disease phenotypes appear in similar modular styles. Network representations of phenotypes make it possible to explore this hypothesis. We investigated the modularity of a network of genetic disease phenotypes. We computationally extracted phenotype modules and found that the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
