Article
From phenotype to gene: detecting disease-specific gene functional modules via a text-based human disease phenotype network construction.
FEBS letters - 20 Aug 2010
Zhang Shihua, Zhang Shi-Hua, Wu Chao, Li Xia, Chen Xi, Jiang Wei, Gong Bin-Sheng, Li Jiang, Yan Yu-Qing
Abstract excerpt
Currently, some efforts have been devoted to the text analysis of disease phenotype data, and their results indicated that similar disease phenotypes arise from functionally related genes. These related genes work together, as a functional module, to perform a desired cellular function. We constructed a text-based human disease phenotype network and detected 82 disease-specific gene functional modules, each...
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