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Article

Tumour necrosis factor- released by testicular macrophages induces apoptosis of germ cells in autoimmune orchitis

15 May 2008

Abstract excerpt

BACKGROUND: Experimental autoimmune orchitis (EAO) is a model of chronic inflammation and infertility useful for studying testicular immune and germ cell (GC) interactions. In this model, EAO was induced in rats by immunization with testicular homogenate and adjuvants; Control (C) rats were injected with adjuvants. EAO was characterized by an interstitial infiltrate of lymphomonocytes and seminiferous tubule...

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PMID: 18579514
DOI: 10.1093/humrep/den240

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