Article
Alterations in oxidative, inflammatory and apoptotic events in short-lived and long-lived mice testes.
Aging - 1 Jan 2016
Matzkin María Eugenia, Miquet Johanna Gabriela, Fang Yimin, Hill Cristal Monique, Turyn Daniel, Calandra Ricardo Saúl, Bartke Andrzej, Frungieri Mónica Beatriz
Abstract excerpt
Aged testes undergo profound histological and morphological alterations leading to a reduced functionality. Here, we investigated whether variations in longevity affect the development of local inflammatory processes, the oxidative state and the occurrence of apoptotic events in the testis. To this aim, well-established mouse models with delayed (growth hormone releasing hormone-knockout and Ames dwarf mice) or...
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