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Article

Effect of Ras inhibition in hematopoiesis and BCR/ABL leukemogenesis.

Journal of hematology & oncology - 5 Jun 2008

Baum Karina J, Ren Ruibao

Abstract excerpt

Ras small GTPases are activated in many hematopoietic growth factor signaling and in hematological malignancies, but their role in hematopoiesis and leukemogenesis is not completely known. Here we examined the effect of Ras inhibition by a dominant negative mutant of Ras, N17 H-Ras, in adult hema...

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Share to Bone Marrow Cells
Share to Fusion Proteins, bcr-abl
Share to Gene Expression Regulation, Leukemic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hematopoiesis

Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

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Source

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Identifiers

PMID: 18577264
DOI: 10.1186/1756-8722-1-5
PMCID: PMC2438443

Genes

BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18577264-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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