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Article

MUC1 oncoprotein promotes growth and survival of human multiple myeloma cells

1 Jul 2008

Abstract excerpt

The MUC1 oncoprotein is aberrantly expressed in human multiple myeloma cells by mechanisms that are not understood. Moreover, the functional role of MUC1 in multiple myeloma is not known. The present studies demonstrate that the MUC1 gene locus is amplified in multiple myeloma cell lines and in primary cells from patients. The KMS28PE multiple myeloma cell line, which was found to have MUC1 gene amplification,...

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PMID: 18575761
DOI: 10.3892/ijo.33.1.153

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