Is there relationship between the A1166C polymorphism of the angiotensin II receptor AT1 and plasma renin activity, insulin resistance and reduction of blood pressure after angiotensin-converting enzyme inhibitor therapy?

Abstract excerpt

OBJECTIVES: The aim of this study was to assess the relationship between the A1166C polymorphism of the angiotensin AT1 receptor gene and reduction of blood pressure and pulse pressure in patients with mild and moderate arterial hypertension. Moreover, we sought to investigate the impact of insulin resistance and plasma renin activity on blood pressure reduction following treatment with perindopril depending on...

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