Article
Influence of the angiotensin II type 1 receptor gene polymorphism on the effects of perindopril and nitrendipine on arterial stiffness in hypertensive individuals.
Hypertension (Dallas, Tex. : 1979) - 1 Dec 1996
Benetos A, Cambien F, Gautier S, Ricard S, Safar M, Laurent S, Lacolley P, Poirier O, Topouchian J, Asmar R
Abstract excerpt
Angiotensin-converting enzyme inhibitors improve arterial stiffness independently of blood pressure reduction. Since we have recently shown that in hypertensive individuals the A1166C polymorphism of the angiotensin II type 1 receptor (AT1-R) is an independent determinant of aortic stiffness, we...
Topics
- Adult
- Aged
- Angiotensin-Converting Enzyme Inhibitors
- Arteries
- Calcium Channel Blockers
- Cohort Studies
- Female
- Genotype
- Hemodynamics
- Humans
- Hypertension
- Indoles
- Male
- Middle Aged
- Nitrendipine