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Article

A defined transposon mutant library and its use in identifying motility genes in Vibrio cholerae.

Proceedings of the National Academy of Sciences of the United States of America - 24 Jun 2008

Cameron D Ewen, Urbach Jonathan M, Mekalanos John J

Abstract excerpt

Defined mutant libraries allow for efficient genome-scale screening and provide a convenient collection of mutations in almost any nonessential gene of interest. Here, we present a near-saturating transposon insertion library in Vibrio cholerae strain C6706, a clinical isolate belonging to the O1 El Tor biotype responsible for the current cholera pandemic. Automated sequencing analysis of 23,312 mutants allowed...

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Identifiers

PMID: 18574146
DOI: 10.1073/pnas.0803281105
PMCID: PMC2438431

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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