Article
IL1B genetic variation and plasma C-reactive protein level among young adults: the CARDIA study.
Atherosclerosis - 1 Feb 2009
Enquobahrie Daniel A, Rice Kenneth, Williams O Dale, Williams Michelle A, Gross Myron D, Lewis Cora E, Schwartz Stephen M, Siscovick David S
Abstract excerpt
OBJECTIVE: Interleukin-1B (IL1B) modulates C-reactive protein (CRP) expression. However, whether IL1B genetic variation is associated with CRP level is unknown. Further, obesity, a state of low-grade inflammation that influences cellular IL-1 functions may modify this association. METHODS AND RESULTS: Study participants (N=3289), 48% blacks and 52% whites, had CRP level measurements at year 7 and year 15...
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