Article
Interleukin 1B gene polymorphism is associated with baseline C-reactive protein levels in healthy individuals.
European cytokine network - 1 Jan 2000
Eklund Carita, Jahan Farhana, Pessi Tanja, Lehtimäki Terho, Hurme Mikko
Abstract excerpt
C-reactive protein (CRP) is a sensitive marker of inflammation induced by both IL-6 and IL-1. Thus, genetic variation in these genes could be associated with the variety in C-reactive protein levels, and therefore with the severity of the entire inflammatory response. Even a subtle elevation in baseline CRP levels in healthy individuals has been found to significantly increase the risk for cardiovascular...
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